Editorial summaries
Provisional editorial interpretation based on a selected group of reviewed publications. This is not a systematic review of the entire catalogue or a scientific consensus statement.
Editorial summary translated for navigation; original publication language is unchanged.
Experimental and theoretical approaches to conscious processing
Stanislas Dehaene; Jean-Pierre Changeux · 2011 · Neuron
Editorial summary
Reviews conscious access through amplification and widespread availability of neural information in the global neuronal workspace framework.
Limitations
A theoretical synthesis does not fully explain subjective experience.
Open sourceConscious Processing and the Global Neuronal Workspace Hypothesis
George A. Mashour et al. · 2020 · Neuron
Editorial summary
Reviews global neuronal workspace mechanisms across perception, attention, working memory and anesthesia, emphasizing recurrent amplification and information sharing.
Limitations
Competing theoretical accounts remain under investigation.
Open sourceIntegrated information theory (IIT) 4.0: Formulating the properties of phenomenal existence in physical terms
Larissa Albantakis et al. · 2023 · PLOS Computational Biology
Editorial summary
Formalizes integrated information theory using proposed properties of experience, intrinsic information and causal relationships within physical systems.
Limitations
The framework is theoretical, not experimental proof of consciousness.
Open sourceNeural correlates of consciousness: progress and problems
Christof Koch; Marcello Massimini; Melanie Boly; Giulio Tononi · 2016 · Nature Reviews Neuroscience
Editorial summary
Reviews neural correlates and quantitative measures, emphasizing posterior cortical regions and separating experience from task monitoring and reporting.
Limitations
Correlation does not establish causal sufficiency or settle theoretical disagreements.
Open sourceA theoretically based index of consciousness independent of sensory processing and behavior
Adenauer G. Casali et al. · 2013 · Science Translational Medicine
Editorial summary
Introduces an index of stimulation-evoked EEG complexity that distinguished several conscious and unconscious conditions in the studied participants.
Limitations
A physiological index does not directly reveal subjective experience.
Open sourceStratification of unresponsive patients by an independently validated index of brain complexity
Silvia Casarotto et al. · 2016 · Annals of Neurology
Editorial summary
Validated a brain-complexity threshold before identifying some unresponsive patients with values overlapping those measured in conscious benchmark conditions.
Limitations
High complexity cannot independently confirm experience in noncommunicative patients.
Open sourceAdversarial testing of global neuronal workspace and integrated information theories of consciousness
Cogitate Consortium; Oscar Ferrante et al. · 2025 · Nature
Editorial summary
A preregistered multimodal study in 256 participants challenged selected predictions of global neuronal workspace and integrated information theories.
Limitations
It tests specific visual-consciousness predictions, not every claim of either theory.
Open sourceBreakdown of cortical effective connectivity during sleep
Marcello Massimini et al. · 2005 · Science
Editorial summary
Magnetic stimulation and EEG showed that cortical responses during non-REM sleep remained more localized than during quiet wakefulness.
Limitations
These findings do not imply that all sleep lacks conscious experience.
Open sourceConsciousness and Complexity during Unresponsiveness Induced by Propofol, Xenon, and Ketamine
Simone Sarasso et al. · 2015 · Current Biology
Editorial summary
During drug-induced unresponsiveness, ketamine preserved more complex cortical responses than propofol or xenon, separating responsiveness from brain complexity.
Limitations
Drug effects and retrospective reports complicate inferences about subjective experience.
Open sourceThe neural correlates of dreaming
Francesca Siclari et al. · 2017 · Nature Neuroscience
Editorial summary
High-density EEG associated reported dreams with reduced posterior low-frequency activity, while some faster activity correlated with dream contents.
Limitations
Reports after awakening may confound dreaming with dream recall.
Open sourceDetecting awareness in the vegetative state
Adrian M. Owen et al. · 2006 · Science
Editorial summary
In one behaviorally unresponsive patient, instructed mental imagery produced task-specific brain activity resembling healthy volunteers, revealing covert command-following.
Limitations
A single-patient finding cannot establish awareness in all similarly diagnosed patients.
Open sourcePreserved feedforward but impaired top-down processes in the vegetative state
Melanie Boly et al. · 2011 · Science
Editorial summary
During an auditory task, impaired backward frontal-to-temporal connectivity distinguished the vegetative-state group from controls in the studied sample.
Limitations
Model-dependent connectivity estimates are not universally sufficient markers of consciousness.
Open sourceNear-death experience in survivors of cardiac arrest: a prospective study in the Netherlands
Pim van Lommel et al. · 2001 · The Lancet
Editorial summary
Interviews with 344 cardiac-arrest survivors examined near-death experiences and subsequent attitude changes.
Limitations
Recalled experiences cannot establish their timing or independence from brain activity.
Open sourceA qualitative and quantitative study of the incidence, features and aetiology of near death experiences in cardiac arrest survivors
Sam Parnia et al. · 2001 · Resuscitation
Editorial summary
Interviews with 63 cardiac-arrest survivors explored memories, experience features and physiological associations.
Limitations
Few reported experiences, limiting statistical conclusions and physiological interpretation.
Open sourceAWARE-AWAreness during REsuscitation-a prospective study
Sam Parnia et al. · 2014 · Resuscitation
Editorial summary
This multicentre study examined memories after cardiac arrest, with 140 initial and 101 detailed survivor interviews.
Limitations
Survivor selection and few awareness reports limit generalization.
Open sourceAWAreness during REsuscitation - II: A multi-center study of consciousness and awareness in cardiac arrest
Sam Parnia et al. · 2023 · Resuscitation
Editorial summary
Interviews and physiological monitoring explored awareness during resuscitation; none of 28 interviewed survivors identified the visual target.
Limitations
Small survivor samples cannot establish consciousness after irreversible death.
Open sourceSurge of neurophysiological coherence and connectivity in the dying brain
Jimo Borjigin et al. · 2013 · Proceedings of the National Academy of Sciences
Editorial summary
Rat EEG showed briefly increased gamma coordination and connectivity after experimental cardiac arrest.
Limitations
Animal neural signals do not directly demonstrate subjective experience.
Open sourceEnhanced Interplay of Neuronal Coherence and Coupling in the Dying Human Brain
Raul Vicente et al. · 2022 · Frontiers in Aging Neuroscience
Editorial summary
EEG recorded gamma activity and coupling changes around cardiac arrest in one brain-injured patient.
Limitations
A single injured brain cannot establish conscious experience.
Open sourceSurge of neurophysiological coupling and connectivity of gamma oscillations in the dying human brain
Gang Xu et al. · 2023 · Proceedings of the National Academy of Sciences
Editorial summary
Two of four dying patients showed increased gamma activity and connectivity after ventilatory support withdrawal.
Limitations
No subjective reports linked these signals to conscious awareness.
Open sourceReturn of consciousness during ongoing cardiopulmonary resuscitation: A systematic review
Alexander Olaussen et al. · 2015 · Resuscitation
Editorial summary
This systematic review gathered reports of signs of consciousness during ongoing cardiopulmonary resuscitation.
Limitations
Responsiveness during CPR is not evidence of consciousness after irreversible death.
Open sourceConsciousness and the Dying Brain
George A. Mashour et al. · 2024 · Anesthesiology
Editorial summary
This review connects near-death reports with research on electrical activity and connectivity around cardiac or respiratory arrest.
Limitations
Candidate neural correlates do not establish subjective experience.
Open sourceNear-death experiences after cardiac arrest: a scoping review
Joshua G. Kovoor et al. · 2024 · Discover Mental Health
Editorial summary
This scoping review mapped prospective studies, finding varied experience frequencies and assessment methods.
Limitations
Heterogeneity and recall bias limited comparison and prevented meta-analysis.
Open sourceElectromagnetic signals are produced by aqueous nanostructures derived from bacterial DNA sequences
Luc Montagnier et al. · 2009 · Interdisciplinary Sciences: Computational Life Sciences
Editorial summary
The authors report electromagnetic signals in diluted bacterial DNA preparations and propose a resonance mechanism.
Limitations
Independent replication is not established by this abstract.
Open sourceBiophoton emission. New evidence for coherence and DNA as source
F. A. Popp et al. · 1984 · Cell Biophysics
Editorial summary
Cellular photon measurements were interpreted by the authors as evidence for coherence and a contribution from DNA.
Limitations
A 2015 critical review challenges the coherence interpretation.
Open source[Experimental investigations on ultraweak photonemission form biological systems (author's transl)]
B. Ruth and F. A. Popp · 1976 · Zeitschrift für Naturforschung C
Editorial summary
Measurements detected faint photon emission from yeast and seedlings, including changes after chemical treatment.
Limitations
Light emission alone does not demonstrate communication or consciousness.
Open sourcePhoton emission from perturbed and dying organisms: biomedical perspectives
Janusz Slawinski · 2005 · Forschende Komplementärmedizin und Klassische Naturheilkunde
Editorial summary
This review relates biological photon emission to metabolism, physiological stress and biochemical excitation processes.
Limitations
It does not demonstrate consciousness surviving death.
Open sourceUltra-weak photon emission from biological samples: definition, mechanisms, properties, detection and applications
Michal Cifra and Pavel Pospíšil · 2014 · Journal of Photochemistry and Photobiology B: Biology
Editorial summary
The review explains oxidative sources of cellular light and surveys detection methods and physiological monitoring applications.
Limitations
Emission evidence does not establish optical communication or conscious experience.
Open sourceBiophotons, coherence and photocount statistics: A critical review
Michal Cifra et al. · 2015 · Journal of Luminescence
Editorial summary
This critical review finds biological light emission established, but reliable evidence for coherence or nonclassical photon statistics lacking.
Limitations
The assessment covers literature available in 2015.
Open sourceIntegrating information in the brain's EM field: the cemi field theory of consciousness
Johnjoe McFadden · 2020 · Neuroscience of Consciousness
Editorial summary
The cemi model proposes consciousness as information integrated in the brain’s electromagnetic field and outlines testable predictions.
Limitations
A theoretical proposal is not conclusive experimental confirmation.
Open sourceConsciousness: Matter or EMF?
Johnjoe McFadden · 2023 · Frontiers in Human Neuroscience
Editorial summary
This theoretical review advocates electromagnetic accounts of consciousness and compares their explanatory claims with neuronal theories.
Limitations
The comparisons represent the author’s position, not independent confirmation.
Open sourceUltra weak photon emission—a brief review
Rhys R. Mould et al. · 2024 · Frontiers in Physiology
Editorial summary
The authors survey biological photon research, metabolic origins, detection methods and potential applications of ultraweak light emission.
Limitations
Proposed biological roles and applications require separate validation.
Open sourceUltra-weak photon emission: from oxidative metabolism to DNA-based communication: a review of biochemical, biophysical and quantum biological perspectives
Jozsef Bodis et al. · 2026 · Frontiers in Endocrinology
Editorial summary
A review with mouse-embryo measurements examines metabolic photon sources and hypotheses about DNA-related optical signalling.
Limitations
The authors acknowledge that DNA-based biophoton communication remains unproven.
Open sourceUltra-Weak Photon Emission as a By-Product of Mitochondrial Oxidative Metabolism: Mechanisms, Limits, and Implications
Samuel Crowther, Alice Attenborough and Frank Vollmer · 2026 · Nanophotonics
Editorial summary
The review explains mitochondrial photon emission through oxidative chemistry, distinguishing baseline emission from stress-related increases.
Limitations
Its energetic analysis does not cover every cellular light source.
Open sourceImaging of ultraweak spontaneous photon emission from human body displaying diurnal rhythm
Masaki Kobayashi, Daisuke Kikuchi and Hitoshi Okamura · 2009 · PLOS ONE
Editorial summary
Sensitive cameras visualized faint human-body light emission and changes in its intensity across the day.
Limitations
These measurements do not demonstrate an aura or consciousness signal.
Open sourceConsciousness in the universe: a review of the 'Orch OR' theory
Stuart Hameroff; Roger Penrose · 2014 · Physics of Life Reviews
Editorial summary
Reviews the proposed connection between consciousness, quantum processes in microtubules and objective reduction.
Limitations
A theoretical proposal, not a demonstration that quantum processes generate consciousness.
Open sourceImportance of quantum decoherence in brain processes
Max Tegmark · 2000 · Physical Review E
Editorial summary
Calculates rapid decoherence in brain models and challenges a quantum-computational explanation of cognition.
Limitations
The conclusions depend on the modeled states and physical assumptions.
Open sourceQuantum computation in brain microtubules: decoherence and biological feasibility
S. Hagan; S. R. Hameroff; J. A. Tuszyński · 2002 · Physical Review E
Editorial summary
Recalculates microtubule decoherence under different assumptions, responding to criticisms of the Orch OR model.
Limitations
Model calculations do not establish conscious quantum computation in living brains.
Open sourceMicrotubule-Stabilizer Epothilone B Delays Anesthetic-Induced Unconsciousness in Rats
Sana Khan et al. · 2024 · eNeuro
Editorial summary
A microtubule-stabilizing treatment delayed loss of righting reflex during isoflurane anesthesia in rats.
Limitations
An animal behavioral measure does not directly demonstrate quantum consciousness.
Open source